Wednesday. Today. Two more days to Pharmaco Paper! :) Lolx... Not really looking forward but I hope I will be even more confident after tomorrow. Today! I must study later! Now I'm blogging. Just now i was waiting for Joc. Now I'm still waiting so took some time to blog on what I remember... If you want to learn about this anticoagulant drugs then continue to read. :)

Just read about the effects of Warfarin. It's major side effect is Bleeding. It should not be taken when pregnancy. An example of Warfarin is Coumadin. It has a narrow TI(theraputic index). It will have purple toe syndrome which is a net-like skin rash usually on the hands and feet. Alopecia is the loss of hair but its not common. Warfarin's MOA: It inhibits the enzyme Vit K epoxide reductase, which is needed for clotting factors. Therefore, prevents clotting.

Heparin is another kind of anticoagulants. Its MOA: Converts fibrinogen to fibrin. Increases the action of antithrombin3. Its major side effects is also bleeding and after taking it for 5 days, some will have low platelets count (thromobocytopenia). Its available as Heparin Sodium and Low Molecular weight heparins(LMWH).
It should not be taken when pregnancy too.